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Posted by Satak from IP on May 03, 2015 at 12:00:14:

In Reply to: Question to answer thanks posted by Satak on May 03, 2015 at 11:46:27:

Post-extubation stridor (PES) is a frequent complication of intubation, occurring in 2-16% of cases. It is caused by laryngeal oedema that results from damage to the mucosa of the larynx. Mucosal damage is caused by pressure and ischaemia resulting in an inflammatory response. Laryngeal oedema, in severe cases, can lead to acute respiratory compromise necessitating emergency reintubation.

Female gender is a risk factor for both laryngeal oedema and PES. This predisposition has been hypothesised to be due to the female mucous membrane being less resistant to trauma and thinner than that in men.

Other risk factors include
Female gender
Intubation >36 hours
Excessive cuff pressure
Large tube size
Tracheal infection.

Age and asthma are not known risk factors for PES.

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