Re: aspirin Q........PROLONGED PR QT,,,,,,,,

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Posted by kc from IP 196.218.185.244 on December 08, 2013 at 06:57:44:

In Reply to: aspirin Q........PROLONGED PR QT,,,,,,,, posted by img on November 30, 2013 at 13:22:33:

About the lipid form qs. rem the foll. chart-
pKa-Ph +3 +2 +1 0 -1 -2 -3
%protonated 99.9 99 90 50 10 1 0.1
i.e when pKa=pH, 50% is protonated (charged) and 50% is nonprotonated (uncharged). So with pka=3.5
and pH=2.5, pKa-pH=3.5-2.5=+1.0 which is 90% protonated.

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