Acetaminophen toxicity

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Posted by Anuj from IP 152.163.100.14 on February 24, 2012 at 08:06:11:

Acetaminophen toxicity-
Kaplan(gen.priciples-Pathology)
Acetaminophen overdoses can be treated with sulfer agents to REDUCE
glutation in the liver(????),
Why to reduce it????
When,Glutathion is necessary for conjugation of Acetaminophen (Ac) to
harmless conjugates( Ac-mercapturate)
sulfer agents also form other harmless conjugates.
Pl. clear my doubt?
With sincere thanks!!!!

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