Let's do Pathology cases-13

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Posted by JK from IP 129.252.69.45 on July 17, 2008 at 15:35:32:

13. Which one of the the following situation describes a major risk factor for early-onset familial Alzheimer disease?

A. Expansion of CAG trinucleotide repeats on chromosome 4
B. Ingestion of 1-methyl-4-phenyl-tetrahydrobiopteridine
C. Mutations in the genes encoding for presenilins
D. Mutations in the superoxide dismutase 1 gene
E. The presence of the E4 isotype of apolipoprotein E


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