NBME 1 - Section 1- thanks for responce

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Posted by Nader from IP 200.122.153.250 on April 30, 2006 at 21:44:15:

After a full course of immunization with a new vaccine consisting of a recombinant polypeptide. 10% of adults fail to make antibody to the polypeptide. The nonresponders have an increased frequency of one HLA type. What is the most likely explanation for the failure of this group to respond to immunization?
A)Failure of B lymphocytes to recognize the plypeptide.
B)Failure of T lymphocytes to recognize the polypeptide.
C)Lack of class I MHC presentation of the polypeptide.
D)Lack of class II MHC presentation of the polypeptide.

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