Posted by mike from IP 24.239.129.200 on February 28, 2006 at 13:29:04:
1-Three to five days after a viral illness, a 4-year-old child develops pernicious vomiting, lethargy progressing to coma, and hepatomegaly. A liver biopsy would likely show
A. hemosiderin
B. microvesicular steatosis
C. normal histology
D. Periodic acid-Schiff (PAS)-positive cytoplasmic granules
E. rhodamine-positive cytoplasmic granules
2-Three days following a viral illness, a 3-year-old child develops severe vomiting and irritability, followed by lethargy. The concerned parents take the child to the emergency room. Physical examination is remarkable for hepatomegaly. The child is admitted to the hospital, but over the next 24 hours, coma develops, and there is a marked elevation in serum ammonia levels. Electron microscopy of brain or liver would most likely reveal profound alterations in which of the following cellular organelles?
A. Centromeres
B. Cilia
C. Mitochondria
D. Peroxisomes
E. Ribosomes